ERO1LB anticorps (AA 34-230)

N° du produit ABIN6140294

Détail du produit anti-ERO1LB anticorps

Antigène: ERO1LB (ERO1-Like beta (ERO1LB))

Épitope: AA 34-230

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERO1LB est non-conjugé

Application: Western Blotting (WB)

Séquence: QVTGVLDDCL CDIDSIDNFN TYKIFPKIKK LQERDYFRYY KVNLKRPCPF WAEDGHCSIK DCHVEPCPES KIPVGIKAGH SNKYLKMANN TKELEDCEQA NKLGAINSTL SNQSKEAFID WARYDDSRDH FCELDDERSP AAQYVDLLLN PERYTGYKGT SAWRVWNSIY EENCFKPRSV YRPLNPLAPS RGEDDGE

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 34-230 of human ERO1LB (NP_063944.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ERO1LB

Antigène: ERO1LB (ERO1-Like beta (ERO1LB))

Autre désignation: ERO1LB (ERO1LB Produits)

Synonymes: anticorps RGD1563548, anticorps 1300013B24Rik, anticorps 1700065B09Rik, anticorps AI447560, anticorps ero1-beta, anticorps endoplasmic reticulum oxidoreductase 1 beta, anticorps ERO1-like beta (S. cerevisiae), anticorps Ero1b, anticorps ERO1B, anticorps Ero1lb

Sujet: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50 % of P4HB reoxidation rate, as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10 %. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.,ERO1B,ERO1LB,Ero1beta,Signal Transduction,ERO1LB

Poids moléculaire: 16 kDa/53 kDa

ID gène: 56605

UniProt: Q86YB8

Pathways: SARS-CoV-2 Protein Interactome