GSTM4 anticorps (AA 1-218)

N° du produit ABIN6141472

Détail du produit anti-GSTM4 anticorps

Antigène: GSTM4 (Glutathione S-Transferase mu 4 (GSTM4))

Épitope: AA 1-218

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM4 est non-conjugé

Application: Western Blotting (WB)

Séquence: MSMTLGYWDI RGLAHAIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGAHKI TQSNAILCYI ARKHNLCGET EEEKIRVDIL ENQAMDVSNQ LARVCYSPDF EKLKPEYLEE LPTMMQHFSQ FLGKRPWFVG DKITFVDFLA YDVLDLHRIF EPNCLDAFPN LKDFISRFEG LEKISAYMKS SRFLPKPLYT RVAVWGNK

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human GSTM4 (NP_000841.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GSTM4

Antigène: GSTM4 (Glutathione S-Transferase mu 4 (GSTM4))

Autre désignation: GSTM4 (GSTM4 Produits)

Synonymes: anticorps GSTM4-4, anticorps GTM4, anticorps 1110004G14Rik, anticorps GSTM7-7, anticorps Gstb-4, anticorps Gstb4, anticorps glutathione S-transferase mu 4, anticorps glutathione S-transferase, mu 4, anticorps GSTM4, anticorps Gstm4

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified.,GSTM4,GSTM4-4,GTM4,Cancer,Signal Transduction,Endocrine & Metabolism,Drug metabolism,GSTM4

Poids moléculaire: 18 kDa/22 kDa/25 kDa

ID gène: 2948

UniProt: Q03013