KRT6A anticorps (AA 305-564)

N° du produit ABIN6143033

Détail du produit anti-KRT6A anticorps

Antigène: KRT6A (Keratin 6A (KRT6A))

Épitope: AA 305-564

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KRT6A est non-conjugé

Application: Western Blotting (WB)

Séquence: ELSQMQTHIS DTSVVLSMDN NRNLDLDSII AEVKAQYEEI AQRSRAEAES WYQTKYEELQ VTAGRHGDDL RNTKQEIAEI NRMIQRLRSE IDHVKKQCAN LQAAIADAEQ RGEMALKDAK NKLEGLEDAL QKAKQDLARL LKEYQELMNV KLALDVEIAT YRKLLEGEEC RLNGEGVGQV NISVVQSTVS SGYGGASGVG SGLGLGGGSS YSYGSGLGVG GGFSSSSGRA IGGGLSSVGG GSSTIKYTTT SSSSRKSYKH

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 305-564 of human Cytokeratin 6 (KRT6) (NP_005545.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KRT6A

Antigène: KRT6A (Keratin 6A (KRT6A))

Autre désignation: KRT6A (KRT6A Produits)

Synonymes: anticorps CK6A, anticorps CK6C, anticorps CK6D, anticorps K6A, anticorps K6C, anticorps K6D, anticorps KRT6C, anticorps KRT6D, anticorps 2310016L08Rik, anticorps Krt2-6a, anticorps Krt2-6c, anticorps MK6a, anticorps mK6[a], anticorps CK-6A, anticorps Krt6a, anticorps KRT6A, anticorps keratin 6A, anticorps similar to keratin complex 2, basic, gene 6a, anticorps keratin, type II cytoskeletal 6A, anticorps KRT6A, anticorps Krt6a, anticorps LOC683313, anticorps LOC101112304

Sujet: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.,KRT6A,CK-6C,CK-6E,CK6A,CK6C,CK6D,K6A,K6C,K6D,KRT6C,KRT6D,PC3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Cytokeratin,Keratin,KRT6A

Poids moléculaire: 60 kDa

ID gène: 3853

UniProt: P02538