MTOR anticorps (AA 2400-2500)

N° du produit ABIN6144170

Cet anticorps anti-MTOR est un anticorps Lapin Polyclonal détectant MTOR dans WB et IF. Adapté pour Humain.

Aperçu rapide pour MTOR anticorps (AA 2400-2500) (ABIN6144170)

Antigène: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTOR est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-MTOR anticorps

Épitope: AA 2400-2500

Séquence: CHTVMEVLRE HKDSVMAVLE AFVYDPLLNW RLMDTNTKGN KRSRTRTDSY SAGQSVEILD GVELGEPAHK KTGTTVPESI HSFIGDGLVK PEALNKKAIQ I

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 2400-2500 of human mTOR (NP_004949.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MTOR

Antigène: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Autre désignation: mTOR

Sujet: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.,FRAP,FRAP1,FRAP2,RAFT1,RAPT1,SKS,mTOR,MTOR,Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Cell Cycle,Cell cycle inhibitors,TGF-b-Smad Signaling Pathway,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Warburg Effect,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,Cardiovascular,Angiogenesis,Heart,Cardiogenesis,Regulators,mTOR

Poids moléculaire: 288 kDa

ID gène: 2475

UniProt: P42345

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, L'effet Warburg