Notch1 anticorps

N° du produit ABIN6144734

Détail du produit anti-Notch1 anticorps

Antigène: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Notch1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide of human Notch1

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Notch1

Antigène: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Autre désignation: NOTCH1 (NOTCH1 Produits)

Synonymes: anticorps notch1, anticorps NOTCH1, anticorps hn1, anticorps tan1, anticorps notch, anticorps xotch, anticorps xnotch, anticorps notch-1, anticorps xnotch1, anticorps TAN1, anticorps hN1, anticorps 9930111A19Rik, anticorps Mis6, anticorps N1, anticorps Tan1, anticorps lin-12, anticorps NOTCH, anticorps Xotch, anticorps notch1-a, anticorps notch 1, anticorps fibropellin-1, anticorps Notch homolog 1, translocation-associated (Drosophila), anticorps Notch homolog 1, translocation-associated, anticorps notch 1 S homeolog, anticorps notch1, anticorps LOC100631526, anticorps NOTCH1, anticorps Notch1, anticorps notch1.S

Sujet: This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma.,AOS5,AOVD1,TAN1,hN1,NOTCH1,Activated NOTCH1,notch 1,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,Notch Signaling Pathway,ESC Pluripotency and Differentiation,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Heart,Cardiogenesis,Neural Stem Cell marker,NOTCH1

Poids moléculaire: 272 kDa

ID gène: 4851

UniProt: P46531

Pathways: Signalisation Notch, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development