TR4 anticorps (AA 240-380)

N° du produit ABIN6222061

Détail du produit anti-TR4 anticorps

Antigène: TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))

Épitope: AA 240-380

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TR4 est non-conjugé

Application: Western Blotting (WB)

Séquence: LIATPTFVAD KDGARQTGLL DPGMLVNIQQ PLIREDGTVL LATDSKAETS QGALGTLANV VTSLANLSES LNNGDTSEIQ PEDQSASEIT RAFDTLAKAL NTTDSSSSPS LADGIDTSGG GSIHVISRDQ STPIIEVEGP L

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human NR2C2 (NP_003289.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TR4

Antigène: TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))

Autre désignation: NR2C2 (NR2C2 Produits)

Synonymes: anticorps TAK1, anticorps TR2R1, anticorps TR4, anticorps hTAK1, anticorps Tr4, anticorps gb:dq017625, anticorps im:6911408, anticorps mKIAA4145, anticorps nuclear receptor subfamily 2 group C member 2, anticorps nuclear receptor subfamily 2, group C, member 2, anticorps NR2C2, anticorps Nr2c2, anticorps nr2c2

Sujet: This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms.,NR2C2,TAK1,TR4,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Cell Biology & Developmental Biology,TGF-b-Smad Signaling Pathway,ESC Pluripotency and Differentiation,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,NR2C2

Poids moléculaire: 65 kDa/67 kDa

ID gène: 7182

UniProt: P49116

Pathways: TCR Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades