PARL anticorps (AA 1-170)

N° du produit ABIN6145228

Détail du produit anti-PARL anticorps

Antigène: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Épitope: AA 1-170

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARL est non-conjugé

Application: Western Blotting (WB)

Séquence: MAWRGWAQRG WGCGQAWGAS VGGRSCEELT AVLTPPQLLG RRFNFFIQQK CGFRKAPRKV EPRRSDPGTS GEAYKRSALI PPVEETVFYP SPYPIRSLIK PLFFTVGFTG CAFGSAAIWQ YESLKSRVQS YFDGIKADWL DSIRPQKEGD FRKEINKWWN NLSDGQRTVT

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human PARL (NP_001032728.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PARL

Antigène: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Autre désignation: PARL (PARL Produits)

Synonymes: anticorps PSARL, anticorps PSARL1, anticorps PSENIP2, anticorps RHBDS1, anticorps D16Ertd607e, anticorps PRO2207, anticorps Psarl, anticorps parl, anticorps zgc:112986, anticorps presenilin associated rhomboid like, anticorps presenilin associated, rhomboid-like, anticorps presenilin associated, rhomboid-like a, anticorps PARL, anticorps Parl, anticorps parla

Sujet: This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.,PARL,PRO2207,PSARL,PSARL1,PSENIP2,RHBDS1,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,PARL

Poids moléculaire: 36 kDa/42 kDa

ID gène: 55486

UniProt: Q9H300

Pathways: Autophagy