PTPRF anticorps (AA 30-190)

N° du produit ABIN6146462

Détail du produit anti-PTPRF anticorps

Antigène: PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))

Épitope: AA 30-190

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPRF est non-conjugé

Application: Western Blotting (WB)

Séquence: DSKPVFIKVP EDQTGLSGGV ASFVCQATGE PKPRITWMKK GKKVSSQRFE VIEFDDGAGS VLRIQPLRVQ RDEAIYECTA TNSLGEINTS AKLSVLEEEQ LPPGFPSIDM GPQLKVVEKA RTATMLCAAG GNPDPEISWF KDFLPVDPAT SNGRIKQLRS G

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 30-190 of human PTPRF (NP_569707.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PTPRF

Antigène: PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))

Autre désignation: PTPRF (PTPRF Produits)

Synonymes: anticorps LAR, anticorps AA591035, anticorps LARS, anticorps RPTP-LAR, anticorps LARFN5C, anticorps zf-LAR, anticorps protein tyrosine phosphatase, receptor type F, anticorps protein tyrosine phosphatase, receptor type, F, anticorps protein tyrosine phosphatase, receptor type, f, a, anticorps PTPRF, anticorps Ptprf, anticorps ptprfa

Sujet: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.,PTPRF,BNAH2,LAR,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Cell Type Marker,Neuron marker,Synapse marker,PTPRF

Poids moléculaire: 211 kDa/212 kDa

ID gène: 5792

UniProt: P10586

Pathways: EGFR Signaling Pathway