RELB anticorps (AA 380-579)
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- Antigène Voir toutes RELB Anticorps
- RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))
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Épitope
- AA 380-579
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RELB est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- FLQRLTDGVC SEPLPFTYLP RDHDSYGVDK KRKRGMPDVL GELNSSDPHG IESKRRKKKP AILDHFLPNH GSGPFLPPSA LLPDPDFFSG TVSLPGLEPP GGPDLLDDGF AYDPTAPTLF TMLDLLPPAP PHASAVVCSG GAGAVVGETP GPEPLTLDSY QAPGPGDGGT ASLVGSNMFP NHYREAAFGG GLLSPGPEAT
- Réactivité croisée
- Humain, Souris
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 380-579 of human RELB (NP_006500.2).
- Isotype
- IgG
- Top Product
- Discover our top product RELB Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000
- Commentaires
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))
- Autre désignation
- RELB (RELB Produits)
- Synonymes
- anticorps shep, anticorps I-REL, anticorps IREL, anticorps REL-B, anticorps XRelB, anticorps relb-A, anticorps GC-rich, anticorps avian reticuloendotheliosis viral (v-rel) oncogene related B, anticorps RELB proto-oncogene, NF-kB subunit, anticorps v-rel avian reticuloendotheliosis viral oncogene homolog B S homeolog, anticorps Relb, anticorps RELB, anticorps relb.S
- Sujet
- NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric RelB-p50 and RelB-p52 complexes are transcriptional activators. RELB neither associates with DNA nor with RELA/p65 or REL. Stimulates promoter activity in the presence of NFKB2/p49. Increased repression of the heterodimer is seen in the presence of NFKB2/p52. Is required for both T and B lymphocyte maturation and function.,RELB,I-REL,IREL,REL-B,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,RELB
- Poids moléculaire
- 62 kDa
- ID gène
- 5971
- UniProt
- Q01201
- Pathways
- Signalisation NF-kappaB, Signalisation RTK
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