ERCC3 anticorps (AA 242-261)

N° du produit ABIN614756

L’anticorps anti-ERCC3 Monoclonal Souris est utilisé pour la détection de ERCC3 dans des échantillons de Humain. Il a été validé pour WB, IP, IHC (p) et EIA.

Aperçu rapide pour ERCC3 anticorps (AA 242-261) (ABIN614756)

Antigène: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ERCC3 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 3G4

Détail du produit anti-ERCC3 anticorps

Épitope: AA 242-261

Specificité: Recognizes an epitope located between aa242-261 of ERCC-3 (largest subunit of TFIIH).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein G Chromatography

Immunogène: Synthetic peptide corresponding to aa242-261 of Human ERCC-3.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 0.1 M Tris-HCl, pH 7.5.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (Add 40-50% Glycerol) at -20 °C for longer.

Détails sur ERCC3

Antigène: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Autre désignation: ERCC3

Sujet: ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kD subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.Synonyms: BTF2-p89, Basic transcription factor 2 89 kDa subunit, DNA excision repair protein ERCC-3, DNA repair protein complementing XP-B cells, ERCC-3, TFIIH 89 kDa subunit, TFIIH basal transcription factor complex helicase XPB subunit, XPB, XPBC, Xeroderma pigmentosum group B-complementing protein

ID gène: 2071

NCBI Accession: NP_000113

UniProt: P19447

Pathways: Réparation de l'ADN