SLC7A11 anticorps (AA 150-250)

N° du produit ABIN6148046

Détail du produit anti-SLC7A11 anticorps

Antigène: SLC7A11 (Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))

Épitope: AA 150-250

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC7A11 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: ILEPFFIQCE IPELAIKLIT AVGITVVMVL NSMSVSWSAR IQIFLTFCKL TAILIIIVPG VMQLIKGQTQ NFKDAFSGRD SSITRLPLAF YYGMYAYAGW F

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC7A11/xCT (NP_055146.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SLC7A11

Antigène: SLC7A11 (Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))

Autre désignation: SLC7A11 (SLC7A11 Produits)

Synonymes: anticorps SLC7A11, anticorps DKFZp468E122, anticorps CCBR1, anticorps xCT, anticorps 9930009M05Rik, anticorps AI451155, anticorps sut, anticorps solute carrier family 7 member 11, anticorps solute carrier family 7, (cationic amino acid transporter, y+ system) member 11, anticorps solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, anticorps SLC7A11, anticorps Slc7a11

Sujet: This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.,SLC7A11,CCBR1,xCT,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,SLC7A11

Poids moléculaire: 55 kDa

ID gène: 23657

UniProt: Q9UPY5