SLC7A11 anticorps

N° du produit ABIN7270482

Détail du produit anti-SLC7A11 anticorps

Antigène: SLC7A11 (Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SLC7A11 est non-conjugé

Application: Western Blotting (WB)

Fonction: SLC7A11/xCT Rabbit mAb

Réactivité croisée: Humain

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human SLC7A11/xCT

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SLC7A11

Antigène: SLC7A11 (Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))

Autre désignation: SLC7A11 (SLC7A11 Produits)

Synonymes: anticorps SLC7A11, anticorps DKFZp468E122, anticorps CCBR1, anticorps xCT, anticorps 9930009M05Rik, anticorps AI451155, anticorps sut, anticorps solute carrier family 7 member 11, anticorps solute carrier family 7, (cationic amino acid transporter, y+ system) member 11, anticorps solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, anticorps SLC7A11, anticorps Slc7a11

Sujet: This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011],CCBR1, xCT,Amino acid metabolism,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Signal Transduction,SLC7A11

Poids moléculaire: 55kDa

ID gène: 23657

UniProt: Q9UPY5