Spindlin 1 anticorps (AA 1-262)

N° du produit ABIN6221556

Détail du produit anti-Spindlin 1 anticorps

Antigène: Spindlin 1 (SPIN1)

Épitope: AA 1-262

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Spindlin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MKTPFGKTPG QRSRADAGHA GVSANMMKKR TSHKKHRSSV GPSKPVSQPR RNIVGCRIQH GWKEGNGPVT QWKGTVLDQV PVNPSLYLIK YDGFDCVYGL ELNKDERVSA LEVLPDRVAT SRISDAHLAD TMIGKAVEHM FETEDGSKDE WRGMVLARAP VMNTWFYITY EKDPVLYMYQ LLDDYKEGDL RIMPDSNDSP PAEREPGEVV DSLVGKQVEY AKEDGSKRTG MVIHQVEAKP SVYFIKFDDD FHIYVYDLVK TS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-262 of human SPIN1 (NP_006708.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Spindlin 1

Antigène: Spindlin 1 (SPIN1)

Autre désignation: SPIN1 (SPIN1 Produits)

Synonymes: anticorps SPIN, anticorps AA553322, anticorps AA673430, anticorps Spin, anticorps spin, anticorps spindlin, anticorps MGC115436, anticorps Spindlin-1, anticorps DKFZp459K085, anticorps spindlin 1, anticorps spindlin 1 L homeolog, anticorps SPIN1, anticorps Spin1, anticorps spin1, anticorps spin1.L

Sujet: Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a and acts as an activator of Wnt signaling pathway downstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway. Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes. May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.,SPIN1,SPIN,TDRD24,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,SPIN1

Poids moléculaire: 29 kDa

ID gène: 10927

UniProt: Q9Y657