SPP1
Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Mouton, Chévre
WB, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB,1:500 - 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Wu, Wang, Ji, Ou, Xia, Zhang, Zhao: "C4orf7 modulates osteogenesis and adipogenesis of human periodontal ligament cells." dans: American journal of translational research, Vol. 9, Issue 12, pp. 5708-5718, (2017) (PubMed).
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.,BNSP,BSPI,ETA-1,OPN,Osteopontin,SPP1,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,Immunology & Inflammation,Cytokines,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Angiogenesis,SPP1