PAFAH1B1 anticorps (C-Term)

N° du produit ABIN614917

Détail du produit anti-PAFAH1B1 anticorps

Antigène: PAFAH1B1 (Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PAFAH1B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: TGSVDQTVKV WECR

Specificité: This antibody detects PAFAH1B1 / LIS1.

Réactivité croisée (Details): Species reactivity (expected):Cow, Dog, Mouse, Pig, RatSpecies reactivity (tested):Human

Purification: Immunoaffinity chromatography

Immunogène: Peptide from (C-term) of the protein sequence according to NP_000421. Genename: PAFAH1B1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris buffered saline, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur PAFAH1B1

Antigène: PAFAH1B1 (Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))

Autre désignation: PAFAH1B1 / LIS1 (PAFAH1B1 Produits)

Synonymes: anticorps LIS1, anticorps LIS2, anticorps MDCR, anticorps MDS, anticorps PAFAH, anticorps LIS-1, anticorps Lis1, anticorps MMS10-U, anticorps Mdsh, anticorps Ms10u, anticorps Pafaha, anticorps lis2, anticorps mdcr, anticorps mds, anticorps pafah, anticorps pafah1b1-b, anticorps PAFAHA, anticorps Lis1a, anticorps platelet activating factor acetylhydrolase 1b regulatory subunit 1, anticorps platelet-activating factor acetylhydrolase, isoform 1b, subunit 1, anticorps platelet-activating factor acetylhydrolase 1b, regulatory subunit 1, anticorps platelet activating factor acetylhydrolase 1b regulatory subunit 1 L homeolog, anticorps platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a, anticorps platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b, anticorps PAFAH1B1, anticorps Pafah1b1, anticorps pafah1b1.L, anticorps pafah1b1a, anticorps pafah1b1b

Sujet: PAFAH1B1 was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. PAFAH1B1 encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum.Synonyms: LIS-1, Lissencephaly-1 protein, MDCR, MDS, PAF acetylhydrolase 45 kDa subunit, PAF-AH alpha, PAFAH alpha, PAFAHA, Platelet-activating factor acetylhydrolase IB subunit alpha

ID gène: 5048

NCBI Accession: NP_000421

UniProt: P43034

Pathways: M Phase, Regulation of Cell Size