GRIA4 anticorps (Internal Region)

N° du produit ABIN614977

Détail du produit anti-GRIA4 anticorps

Antigène: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIA4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: C-KKLDQREYPG SETP

Specificité: This antibody detects Glutamate receptor 4 / GLUR4 (Internal).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat and Bovine.
Species reactivity (tested):Human.

Purification: Immunoaffinity chromatography

Immunogène: Peptide with from the internal region of the protein sequence according to NP_000820.3, NP_001070711.1, NP_001070712.1 Genename: GRIA4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % sodium azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GRIA4

Antigène: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Autre désignation: Glutamate Receptor 4 / GLUR4 (GRIA4 Produits)

Synonymes: anticorps GLUR4, anticorps GLUR4C, anticorps GLURD, anticorps GluA4, anticorps GluR4, anticorps GluR4d, anticorps GLUR4/D, anticorps glur4, anticorps GluR-D, anticorps Glur-4, anticorps Glur4, anticorps Gluralpha4, anticorps spkw1, anticorps DKFZp459P0616, anticorps glur4a, anticorps gria4, anticorps iGluR4, anticorps ZfGluR4b, anticorps fj46g06, anticorps glur4b, anticorps wu:fj46g06, anticorps glutamate ionotropic receptor AMPA type subunit 4, anticorps glutamate receptor, ionotropic, AMPA 4, anticorps glutamate receptor, ionotropic, AMPA4 (alpha 4), anticorps glutamate receptor, ionotropic, AMPA 4a, anticorps glutamate receptor, ionotropic, AMPA 4b, anticorps GRIA4, anticorps gria4, anticorps Gria4, anticorps gria4a, anticorps gria4b

Sujet: Human glutamate receptor 4 (GRIA4) is a new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. Binding studies showed that human GRIA4 transfected into simian kidney cells (COS-1) exhibits high specific binding for[3H](RS)-alpha-amino- 3-hydroxy-5-methylisoxazole-4-propionic acid ([3H]AMPA) but not [3H]kainate. Ion substitution experiments indicate that hGluR4 receptor-linked ion channels in their homomeric state are permeable to both CA2+ and Na+ ions. Immunoprecipitation studies suggest that GRIA1 exists in situ in the form of a pentamer.Synonyms: AMPA-selective glutamate receptor 4, GRIA4, GluA4, GluR-4, GluR-D, Glutamate receptor ionotropic AMPA4

ID gène: 2893

NCBI Accession: NP_000820

UniProt: P48058

Pathways: Signalisation PI3K-Akt