anticorps fb08f03, anticorps fj42c03, anticorps zgc:73244, anticorps zgc:77637, anticorps wu:fb08f03, anticorps wu:fj42c03, anticorps HCRP1, anticorps PQBP2, anticorps SPG53, anticorps 2210018P21Rik, anticorps 4930592A21Rik, anticorps AW261445, anticorps D8Ertd531e, anticorps vacuolar protein sorting 37A, anticorps VPS37A, ESCRT-I subunit, anticorps vacuolar protein sorting 37 homolog A, anticorps vacuolar protein sorting 37 homolog A L homeolog, anticorps vps37a, anticorps VPS37A, anticorps vps37a.L, anticorps Vps37a
Sujet
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.,VPS37A,HCRP1,PQBP2,SPG53,Signal Transduction,VPS37A