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Prostaglandin D2 Receptor 2 (PTGDR2) (N-Term) anticorps

PTGDR2 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN615056
  • Antigène Voir toutes Prostaglandin D2 Receptor 2 (PTGDR2) Anticorps
    Prostaglandin D2 Receptor 2 (PTGDR2)
    Épitope
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 65
    • 23
    • 12
    • 4
    • 3
    Humain, Souris, Rat
    Hôte
    • 52
    • 13
    • 1
    Lapin
    Clonalité
    • 52
    • 14
    Polyclonal
    Conjugué
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Inconjugué
    Application
    • 27
    • 17
    • 14
    • 13
    • 13
    • 12
    • 7
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to G Protein-Coupled Receptor GPR44 (CRTH2).
    Purification
    Immunoaffinity Chromatography
    Immunogène
    GPR44 antibody was raised against synthetic peptide Genename: GPR44
    Top Product
    Discover our top product PTGDR2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1,0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    Prostaglandin D2 Receptor 2 (PTGDR2)
    Autre désignation
    CD294 / GPR44 (PTGDR2 Produits)
    Synonymes
    anticorps CD294, anticorps CRTH2, anticorps DL1R, anticorps DP2, anticorps GPR44, anticorps Crth2, anticorps Grp45, anticorps Ptgdr2, anticorps Gpr44, anticorps prostaglandin D2 receptor 2, anticorps PTGDR2, anticorps Ptgdr2
    Sujet
    GPR44, also called CRTH2, is a Prostanoid Receptor that binds prostaglandin D2. PGD2 signals through CRTH2 to induce Th2, eosinophil, and basophil chemotaxis in a G-alpha(i) dependent manner. CRTH2 may play a role in mast cell-mediated immune responses such as those involved in allergic reactions. This receptor is upregulated in activated T helper-2 (Th2) cells, peripheral blood basophils, and eosinophils, but not in Th1 lineage cells. It may be a useful marker for Th2 and Tc2 cells.Synonyms: CRTH2, Chemoattractant receptor-homologous molecule expressed on Th2 cells, DL1R, Putative G-protein coupled receptor 44
    ID gène
    11251
    NCBI Accession
    NP_004769
    UniProt
    Q9Y5Y4
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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