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Prostaglandin D2 Receptor 2 (PTGDR2) anticorps

PTGDR2 Reactivité: Humain FACS Hôte: Rat Monoclonal BM16 unconjugated
N° du produit ABIN7505893
  • Antigène Voir toutes Prostaglandin D2 Receptor 2 (PTGDR2) Anticorps
    Prostaglandin D2 Receptor 2 (PTGDR2)
    Reactivité
    • 65
    • 24
    • 13
    • 4
    • 3
    Humain
    Hôte
    • 53
    • 12
    • 1
    Rat
    Clonalité
    • 53
    • 13
    Monoclonal
    Conjugué
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Inconjugué
    Application
    • 28
    • 18
    • 14
    • 13
    • 13
    • 11
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Fonction
    Anti-Hu CD294 Purified
    Specificité
    The rat monoclonal antibody BM16 recognizes an extracellular epitope of CD294 / CRTH2 (prostaglandin D2 receptor 2), a G-protein-coupled seven-transmembrane protein expressed on Th2 cells, peripheral blood basophils and eosinophils.
    Purification
    Purified by protein-G affinity chromatography.
    Immunogène
    Human CD294 transfected rat cell line TART/B19-12.10
    Clone
    BM16
    Isotype
    IgG2a
    Top Product
    Discover our top product PTGDR2 Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    Prostaglandin D2 Receptor 2 (PTGDR2)
    Autre désignation
    CD294 (PTGDR2 Produits)
    Synonymes
    anticorps CD294, anticorps CRTH2, anticorps DL1R, anticorps DP2, anticorps GPR44, anticorps Crth2, anticorps Grp45, anticorps Ptgdr2, anticorps Gpr44, anticorps prostaglandin D2 receptor 2, anticorps PTGDR2, anticorps Ptgdr2
    Sujet
    Prostaglandin D2 receptor 2,CD294 (prostaglandin D2 receptor 2) is a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells, but also on eosinophils and basophils. It mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of CD294 gene have been associated with asthma susceptibility. Outside the immune system CD294 is expressed e.g. in gut, heart, and brain. The intracellular C terminal tail contains sites for phosphorylation by protein kinase C.,DP2, PTGDR2, DL1R, CRTH2, GPR44
    ID gène
    11251
    UniProt
    Q9Y5Y4
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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