BAK1 anticorps (N-Term)

N° du produit ABIN615093

Cet anticorps anti-BAK1 Polyclonal Lapin (ABIN615093) détecte spécifiquement BAK1 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Hamster.

Aperçu rapide pour BAK1 anticorps (N-Term) (ABIN615093)

Antigène: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Reactivité: Humain, Souris, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAK1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BAK1 anticorps

Épitope: N-Term

Specificité: This antibody recognizes BCL2-antagonist/killer 1 (BAK1).

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide derived from N-terminal of Human Bcl-2-like 7. Genename: BAK1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Détails sur BAK1

Antigène: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Autre désignation: Bcl-2-Like 7

Sujet: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bak, a pro-apoptotic Bcl-2 family member, is an oligomeric protein that localizes to the mitochondria. It is thought to share significant functional homology with Bax, another pro-apoptotic Bcl-2 family member, as disruption of bak or bax has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking bak and bax show decreased apoptotic capability.Synonyms: Apoptosis regulator BAK, BAK, BAK1, BCL2L7, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 7, Bcl2-L-7, CDN1, cell death inhibitor 1

ID gène: 578

NCBI Accession: NP_001179

UniProt: Q16611

Pathways: Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response