Cyclin A anticorps (CF®594)
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- Antigène Voir toutes Cyclin A (CCNA2) Anticorps
- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
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Reactivité
- Humain, Souris, Boeuf (Vache), Singe, Green Monkey, Vison
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Cyclin A est conjugé à/à la CF®594
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS)
- Fonction
- Mouse Monoclonal anti-CyclinA2 (E67), CF594 Conjugate
- Attributs du produit
- This antibody recognizes a protein of 54 kDa, which is identified as cyclin A. Its epitope is located amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk's) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk's. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Full length bovine Cyclin A protein
- Clone
- E67
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CCNA2 Anticorps primaire
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- Indications d'application
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Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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K-562 and HeLa Cells
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
- Autre désignation
- CyclinA2 (CCNA2 Produits)
- Synonymes
- anticorps CCN1, anticorps CCNA, anticorps AA408589, anticorps Ccn-1, anticorps Ccn1, anticorps Ccna, anticorps CycA2, anticorps Cyca, anticorps cb671, anticorps chunp6924, anticorps wu:fi36f03, anticorps CYCA, anticorps Cyclin-A2, anticorps ccna2, anticorps ccn1, anticorps ccna, anticorps ccna1, anticorps Cyclin-A, anticorps cyclinA, anticorps cyclin A2, anticorps cyclin A2 S homeolog, anticorps cyclin A2 L homeolog, anticorps CCNA2, anticorps Ccna2, anticorps ccna2, anticorps ccna2.S, anticorps ccna2.L
- Sujet
- CCN1, CCNA, CCNA2, CCNA2_HUMAN, Cyclin A2
- Poids moléculaire
- 54 kDa
- ID gène
- 890, 58974
- UniProt
- P20248
- Pathways
- Signalisation PI3K-Akt, Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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