BAFF anticorps (Biotin)
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- Antigène Voir toutes BAFF (TNFSF13B) Anticorps
- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BAFF est conjugé à/à la Biotin
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Fonction
- Mouse Monoclonal anti-CD257 / BAFF / TNFSF13B (C257/1638), Biotin Conjugate
- Attributs du produit
- BAFF/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31 kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-? and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors, BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Purified recombinant human full-length CD257 protein
- Clone
- C257-1638
- Isotype
- IgG1
- Top Product
- Discover our top product TNFSF13B Anticorps primaire
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- Indications d'application
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Immunofluorescence 1-2 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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Jurkat cells. Tonsil and lymph node
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Antigène
- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
- Autre désignation
- CD257 / BAFF / TNFSF13B (TNFSF13B Produits)
- Synonymes
- anticorps BAFF, anticorps BLYS, anticorps CD257, anticorps DTL, anticorps TALL-1, anticorps TALL1, anticorps THANK, anticorps TNFSF20, anticorps ZTNF4, anticorps BAFF-R, anticorps BAFFR, anticorps BROMIX, anticorps CD268, anticorps CVID4, anticorps prolixin, anticorps TNFSF13B, anticorps RGD1561519, anticorps RGD1560810, anticorps BLyS, anticorps D8Ertd387e, anticorps zTNF4, anticorps 2010006P15Rik, anticorps Baffr, anticorps Bcmd, anticorps Bcmd-1, anticorps Bcmd1, anticorps Lvis22, anticorps zgc:172115, anticorps TNF superfamily member 13b, anticorps TNF receptor superfamily member 13C, anticorps tumor necrosis factor (ligand) superfamily, member 13b, anticorps tumor necrosis factor receptor superfamily, member 13c, anticorps tumor necrosis factor superfamily member 13b, anticorps TNFSF13B, anticorps TNFRSF13C, anticorps Tnfsf13b, anticorps Tnfrsf13c, anticorps tnfsf13b
- Poids moléculaire
- 31 kDa (Monomer)
- ID gène
- 10673, 525157
- UniProt
- Q9Y275
- Pathways
- Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response
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