GNAQ anticorps (Internal Region)

N° du produit ABIN615969

Détail du produit anti-GNAQ anticorps

Antigène: GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Épitope: AA 162-175, Internal Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GNAQ est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: C-NDLDRVADPA YLPT

Specificité: Recognizes GNAQ / ALPHA-q (aa 162-175).

Réactivité croisée (Details): Species reactivity (expected):Canine (Dog), Pig, Cow.
Species reactivity (tested):Human, Mouse and Rat.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_002063.2. Genename: GNAQ

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GNAQ

Antigène: GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))

Abstract: GNAQ Produits

Synonymes: anticorps si:ch73-270f14.2, anticorps CMC1, anticorps G-ALPHA-q, anticorps GAQ, anticorps SWS, anticorps Galphaq, anticorps Gnaq, anticorps g-alpha-q, anticorps gaq, anticorps gnaqb, anticorps 1110005L02Rik, anticorps 6230401I02Rik, anticorps AA408290, anticorps AW060788, anticorps Dsk1, anticorps Dsk10, anticorps Gq, anticorps GqI, anticorps guanine nucleotide binding protein (G protein), q polypeptide, anticorps G protein subunit alpha q, anticorps guanine nucleotide binding protein (G protein), q polypeptide S homeolog, anticorps guanine nucleotide binding protein, alpha q polypeptide, anticorps gnaq, anticorps GNAQ, anticorps Gnaq, anticorps gnaq.S

Sujet: Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta.Synonyms: GAQ, Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein alpha-q

ID gène: 2776

NCBI Accession: NP_002063

UniProt: P50148

Pathways: Signalistation JAK/STAT, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction