MAGED1 anticorps (C-Term)

N° du produit ABIN616057

Détail du produit anti-MAGED1 anticorps

Antigène: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Épitope: C-Term

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAGED1 est non-conjugé

Application: Western Blotting (WB)

Séquence: C-EAEARAEARN RMGIGDE

Specificité: This antibody detects endogenous level of total Melanoma-associated antigen D1 protein.

Réactivité croisée (Details): Species reactivity (tested):Mouse, Rat

Purification: Affinity-chromatography using epitope-specific peptide

Immunogène: Peptide with sequence derived from Mouse Melanoma-associated antigen D1.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store (in aliquots) at -20 °C.

Détails sur MAGED1

Antigène: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Autre désignation: MAGE-D1 (MAGED1 Produits)

Synonymes: anticorps MAGED1, anticorps DLXIN-1, anticorps NRAGE, anticorps 2810433C11Rik, anticorps 5430405L04Rik, anticorps DXBwg1492e, anticorps Dlixin, anticorps Dlxin-1, anticorps Dlxin1, anticorps MAGE-D1, anticorps mFLJ00163, anticorps Nrage, anticorps MAGE family member D1, anticorps melanoma antigen family D, 1, anticorps melanoma antigen, family D, 1, anticorps MAGED1, anticorps Maged1

Sujet: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.Synonyms: MAGE tumor antigen CCF, MAGED1, Melanoma-associated antigen D1, NRAGE, Neurotrophin receptor-interacting MAGE homolog

Poids moléculaire: 95 kDa

ID gène: 94275

NCBI Accession: NP_062765

UniProt: Q9QYH6

Pathways: Neurotrophin Signaling Pathway