Insulin anticorps (Biotin)

N° du produit ABIN616068

Cet anticorps anti-Insulin Monoclonal Souris conjugué à Biotin (Clone C-PEP-01) (ABIN616068) détecte spécifiquement Insulin dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Insulin anticorps (Biotin) (ABIN616068)

Antigène: Insulin (INS)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Insulin est conjugé à/à la Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: C-PEP-01

Détail du produit anti-Insulin anticorps (Biotin)

Specificité: This antibody reacts specifically with C-peptide, a part of the Proinsulin molecule. Proinsulin consists of the three parts: C-peptide and two long strands of amino acids (alpha and beta chains, later become linked together to form the Insulin molecule). No cross-reactivity with Insulin or other peptide hormones or proteins was observed.

Réactivité croisée (Details): Species reactivity (tested):Human
Also reacts to: Proinsulin

Immunogène: Human C-peptide conjugated to bovine serum albumin

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Détails sur Insulin

Antigène: Insulin (INS)

Autre désignation: Insulin

Sujet: From every molecule of Proinsulin, one molecule of Insulin plus one molecule of C-peptide are produced. C-peptide is released into the blood stream in equal amounts to Insulin.Synonyms: INS

ID gène: 3630

NCBI Accession: NP_000198

UniProt: P01308

Pathways: Signalisation NF-kappaB, Signalisation RTK, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation