LHCGR anticorps (N-Term)

N° du produit ABIN6165116

Détail du produit anti-LHCGR anticorps

Antigène: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Épitope: N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LHCGR est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Fonction: Mouse Monoclonal anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR/1417), Purified, with BSA

Attributs du produit: This antibody recognizes a protein of 78-85 kDa, which is identified as luteinizing hormone/choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Purification: Purified

Immunogène: Recombinant N-terminal fragment of human LHCGR (exact sequence is proprietary)

Clone: LHCGR-1417

Isotype: IgG1 kappa

Information d'application

Indications d'application: Immunohistology (formalin) 0.5-1 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

HepG2 or Jurkat cells. Ovarian Carcinoma

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 200 μg/mL

Buffer: PBS/0.05 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur LHCGR

Antigène: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Autre désignation: Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR Produits)

Synonymes: anticorps HHG, anticorps LCGR, anticorps LGR2, anticorps LH/CG-R, anticorps LH/CGR, anticorps LHR, anticorps LHRHR, anticorps LSH-R, anticorps ULG5, anticorps Gpcr19-rs1, anticorps LH-R, anticorps Lhr, anticorps LSHR, anticorps lhr, anticorps GTHR-II, anticorps zfGTHR-II, anticorps LHCGR, anticorps LOC100222883, anticorps lh-r, anticorps LOC100305044, anticorps luteinizing hormone/choriogonadotropin receptor, anticorps luteinizing hormone/choriogonadotropin receptor L homeolog, anticorps luteinizing hormone receptor, anticorps LHCGR, anticorps Lhcgr, anticorps lhcgr, anticorps lhcgr.L, anticorps lhr, anticorps LOC100305044

Poids moléculaire: 78-85 kDa

ID gène: 3973, 468490

UniProt: P22888

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling