TOX3 anticorps (AA 200-400) (Biotin)
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- Antigène Voir toutes TOX3 Anticorps
- TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))
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Épitope
- AA 200-400
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TOX3 est conjugé à/à la Biotin
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Fonction
- Mouse Monoclonal anti-TOX3 (TOX3/1123), Biotin Conjugate
- Attributs du produit
- This antibody recognizes a 63 kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2 -dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
- Clone
- TOX3-1123
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product TOX3 Anticorps primaire
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- Indications d'application
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Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 or 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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SH-SY5Y, MDA-MB-435 cells. Brain or breast or gastric Carcinoma.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Antigène
- TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))
- Autre désignation
- TOX3 (TOX3 Produits)
- Synonymes
- anticorps TNRC9, anticorps cagf9, anticorps tnrc9, anticorps CAGF9, anticorps 500-9, anticorps BC052044, anticorps C230068E13, anticorps Tnrc9, anticorps TOX high mobility group box family member 3, anticorps TOX3, anticorps tox3, anticorps Tox3
- Sujet
- TOX3, CAG trinucleotide repeat-containing gene F9 protein, CAGF9, TOX high mobility group box family member 3, Trinucleotide repeat containing 9 (TNRC9)
- Poids moléculaire
- 63 kDa
- ID gène
- 27324, 460789
- UniProt
- O15405
- Pathways
- Chromatin Binding
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