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Thyroglobulin anticorps

TG Reactivité: Humain FACS, IHC (f) Hôte: Souris Monoclonal 6E1- unconjugated
N° du produit ABIN6167968
  • Antigène Voir toutes Thyroglobulin (TG) Anticorps
    Thyroglobulin (TG)
    Reactivité
    • 95
    • 36
    • 36
    • 2
    • 1
    Humain
    Hôte
    • 55
    • 39
    • 4
    • 3
    • 1
    • 1
    Souris
    Clonalité
    • 59
    • 41
    Monoclonal
    Conjugué
    • 61
    • 11
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Thyroglobulin est non-conjugé
    Application
    • 37
    • 37
    • 26
    • 25
    • 16
    • 14
    • 12
    • 9
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Fonction
    Mouse Monoclonal anti-Thyroglobulin (6E1), Purified, BSA-free
    Attributs du produit
    Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    Purification
    Purified
    Immunogène
    Human thyroid follicular cells
    Clone
    6E1-
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product TG Anticorps primaire
  • Indications d'application
    Does not react with mouse or rat, others not known
    • Immunohistology formalin-fixed 0.1-0.2 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    Commentaires

    Thyroid

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS (no BSA, no azide)
    Agent conservateur
    Azide free
  • Antigène
    Thyroglobulin (TG)
    Autre désignation
    Thyroglobulin (TG Produits)
    Synonymes
    anticorps TG, anticorps cb717, anticorps AITD3, anticorps TGN, anticorps Tgn, anticorps cog, anticorps thyroglobulin, anticorps TG, anticorps tg, anticorps LOC701526, anticorps LOC701756, anticorps LOC100434297, anticorps Tg
    Sujet
    AITD3, hTG, TDH3, Tg, Tgn
    Poids moléculaire
    660 kDa (Dimeric Form)
    ID gène
    7038, 654591
    UniProt
    P01266
    Pathways
    Thyroid Hormone Synthesis
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