BCL10 anticorps (AA 122-168) (CF®647)
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- Antigène Voir toutes BCL10 Anticorps
- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
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Épitope
- AA 122-168
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BCL10 est conjugé à/à la CF®647
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Fonction
- Mouse Monoclonal anti-BCL-10 (BL10/411), CF647 Conjugate
- Attributs du produit
- BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1,14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF??B activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1,14) translocation, while 55 % of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Human BCL10 recombinant protein (epitope aa122-168)
- Clone
- BL10-411
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product BCL10 Anticorps primaire
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- Indications d'application
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Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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HepG2 cells or Lymphoma.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
- Autre désignation
- BCL-10 (BCL10 Produits)
- Synonymes
- anticorps CARMEN, anticorps CIPER, anticorps CLAP, anticorps c-E10, anticorps mE10, anticorps BCL10, anticorps AI132454, anticorps BCL-10, anticorps C81403, anticorps ME10, anticorps cE10, anticorps bcl10, anticorps B-cell CLL/lymphoma 10, anticorps B-cell lymphoma/leukemia 10-like, anticorps B cell leukemia/lymphoma 10, anticorps B-cell lymphoma/leukemia 10, anticorps BCL10, anticorps Bcl10, anticorps bcl10, anticorps LOC100223183
- Poids moléculaire
- 33 kDa
- ID gène
- 8915, 193516
- UniProt
- O95999
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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