CD79a anticorps (AA 202-216) (CF®405S)
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- Antigène Voir toutes CD79a (CD79A) Anticorps
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
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Épitope
- AA 202-216
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Porc, Singe
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD79a est conjugé à/à la CF®405S
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Fonction
- Mouse Monoclonal anti-CD79a (HM47/A9), CF405S Conjugate
- Attributs du produit
- A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79a protein.
- Clone
- HM47-A9
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD79A Anticorps primaire
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- Indications d'application
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Immunohistology formalin-fixed 0.25-0.5 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- Autre désignation
- CD79a (CD79A Produits)
- Synonymes
- anticorps CD79A, anticorps Ig-alpha, anticorps Iga, anticorps Igalpha, anticorps Ly-54, anticorps Ly54, anticorps mb-1, anticorps IGA, anticorps MB-1, anticorps IG-alpha, anticorps CD79a molecule, anticorps CD79A antigen (immunoglobulin-associated alpha), anticorps Cd79a molecule-like, anticorps CD79A, anticorps Cd79a, anticorps Cd79al
- Poids moléculaire
- 44 kDa
- ID gène
- 973, 631567
- UniProt
- P11912
- Pathways
- BCR Signaling
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