SOX2 anticorps (AA 176-305) (CF®488A)
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- Antigène Voir toutes SOX2 Anticorps
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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Épitope
- AA 176-305
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SOX2 est conjugé à/à la CF®488A
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)
- Fonction
- Mouse Monoclonal anti-SOX2 (SOX2/1792), CF488A Conjugate
- Attributs du produit
- SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Recombinant human SOX2 protein fragment (aa176-305) (exact sequence is proprietary)
- Clone
- SOX2-1792
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product SOX2 Anticorps primaire
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- Indications d'application
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Immunohistology (formalin) 0.5-1 μg/mL
- ELISA 2-4 μg/mL for coating (order Ab without BSA)
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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MCF-7 cells or Cervical carcinoma
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
- Autre désignation
- SOX2 (SOX2 Produits)
- Synonymes
- anticorps ANOP3, anticorps MCOPS3, anticorps RGD1565646, anticorps Sox-2, anticorps lcc, anticorps ysb, anticorps cb236, anticorps wu:fb83g04, anticorps wu:fc14d07, anticorps zgc:65860, anticorps zgc:77389, anticorps SRY-box2, anticorps Xsox-2, anticorps anop3, anticorps mcops3, anticorps sox-2, anticorps SRY-box 2, anticorps SRY box 2, anticorps SRY (sex determining region Y)-box 2, anticorps SRY-box 2 S homeolog, anticorps SOX2, anticorps Sox2, anticorps sox2, anticorps sox2.S
- Sujet
- ANOP3, Delta EF2a, MCOPS3 (Microphthalmia Syndromic type 3), SOX-2, SRY (sex determining region Y) box 2, SRY related HMG box 2, Transcription factor SOX-2, ysb
- Poids moléculaire
- 34 kDa
- ID gène
- 6657, 518438
- UniProt
- P48431
- Pathways
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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