SHP1 anticorps (pTyr564)
Aperçu rapide pour SHP1 anticorps (pTyr564) (ABIN6240989)
Antigène
Voir toutes SHP1 (PTPN6) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr564
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Immunogène
- synthetic peptide
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Stock
- 4 °C,-20 °C
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- SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
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Autre désignation
- SHP-1
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Sujet
- Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
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UniProt
- P29350
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Pathways
- Signalistation JAK/STAT, TCR Signaling, Signalisation TLR, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
Antigène
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