IL28RA anticorps (AA 387-420)

N° du produit ABIN6242856

Détail du produit anti-IL28RA anticorps

Antigène: IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))

Épitope: AA 387-420

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL28RA est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This IL28RA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 387-420 amino acids from the Central region of human IL28RA.

Clone: RB47814

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur IL28RA

Antigène: IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))

Autre désignation: IL28RA (IL28RA Produits)

Synonymes: anticorps IFNLR1, anticorps IL28RA, anticorps crf2/12, anticorps ifnlr, anticorps il-28r1, anticorps il28ra, anticorps licr2, anticorps ifnlr1, anticorps CRF2-12, anticorps Il28ra, anticorps CRF2/12, anticorps IFNLR, anticorps IL-28R1, anticorps LICR2, anticorps RGD1562689, anticorps interferon lambda receptor 1, anticorps interferon, lambda receptor 1, anticorps interferon, lambda receptor 1 L homeolog, anticorps IFNLR1, anticorps ifnlr1, anticorps ifnlr1.L, anticorps Ifnlr1

Sujet: The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus- activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium.

Poids moléculaire: 57653

UniProt: Q8IU57