BMPR2 anticorps (N-Term)

N° du produit ABIN6243512

Détail du produit anti-BMPR2 anticorps

Antigène: BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))

Épitope: AA 27-56, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMPR2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This BMPR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27~56 amino acids from the N-terminal region of human BMPR2.

Clone: RB1806

Isotype: Ig Fraction

Information d'application

Indications d'application: IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur BMPR2

Antigène: BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))

Autre désignation: BMPR2 (BMPR2 Produits)

Synonymes: anticorps BMPR-II, anticorps BMPR3, anticorps BMR2, anticorps BRK-3, anticorps PPH1, anticorps T-ALK, anticorps 2610024H22Rik, anticorps AL117858, anticorps AW546137, anticorps BB189135, anticorps BMP-2, anticorps BMPR-2, anticorps BMPRII, anticorps Gm20272, anticorps Bmpr-II, anticorps bmprii, anticorps bone morphogenetic protein receptor type 2, anticorps bone morphogenetic protein receptor, type II b (serine/threonine kinase), anticorps bone morphogenetic protein receptor, type II (serine/threonine kinase), anticorps BMPR2, anticorps bmpr2b, anticorps Bmpr2

Sujet: BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in BMPR2 have been associated with primary pulmonary hypertension.

Poids moléculaire: 115201

NCBI Accession: NP_001195

UniProt: Q13873

Pathways: Growth Factor Binding