PPP2R5B anticorps (C-Term)

N° du produit ABIN6577726

Détail du produit anti-PPP2R5B anticorps

Antigène: PPP2R5B (Protein Phosphatase 2, Regulatory Subunit B', beta (PPP2R5B))

Épitope: AA 466-500, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP2R5B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PPP2R5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 466-500 amino acids from the C-terminal region of human PPP2R5B.

Clone: RB51478

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:25. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur PPP2R5B

Antigène: PPP2R5B (Protein Phosphatase 2, Regulatory Subunit B', beta (PPP2R5B))

Autre désignation: PPP2R5B (PPP2R5B Produits)

Synonymes: anticorps B56B, anticorps PR61B, anticorps B'beta, anticorps BC026670, anticorps PPP2R5B, anticorps ppp2r5e, anticorps protein phosphatase 2 regulatory subunit B'beta, anticorps protein phosphatase 2, regulatory subunit B', beta, anticorps protein phosphatase 2A regulatory subunit B', anticorps protein phosphatase 2 regulatory subunit B', beta, anticorps protein phosphatase 2 regulatory subunit Bbeta, anticorps PPP2R5B, anticorps Ppp2r5b, anticorps ppp2r5b, anticorps ppp2r5b.L, anticorps PPP2R2B

Sujet: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues.

Poids moléculaire: 57393

UniProt: Q15173

Pathways: Signalisation PI3K-Akt, ER-Nucleus Signaling