Moesin anticorps

N° du produit ABIN6252085

Détail du produit anti-Moesin anticorps

Antigène: Moesin (MSN)

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Moesin est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: Protein G affinity chromatography

Immunogène: Recombinant human protein was used as the immunogen for this Moesin antibody.

Clone: SPM562

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 0.5-1 μg/mL

Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)

Prediluted format : incubate for 30 min at RT (2)

The optimal dilution of the Moesin antibody for each application should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur Moesin

Antigène: Moesin (MSN)

Autre désignation: Moesin (MSN Produits)

Synonymes: anticorps CG10701, anticorps D17, anticorps Dmel\\CG10701, anticorps Dmoe, anticorps EMR1, anticorps ERM, anticorps Emr1, anticorps anon-WO03040301.155, anticorps anon-WO03040301.157, anticorps anon-WO03040301.159, anticorps anon-WO03040301.161, anticorps dMoe, anticorps gma, anticorps l(1)G0067, anticorps l(1)G0323, anticorps l(1)G0404, anticorps l(1)G0415, anticorps moe, anticorps moesin/ezrin/radixin homolog mRNA, anticorps cb567, anticorps rdx, anticorps wu:fb14b03, anticorps zgc:85640, anticorps MSN, anticorps C78546, anticorps moesin, anticorps Moesin, anticorps moesin a, anticorps moesin L homeolog, anticorps MSN, anticorps Moe, anticorps msna, anticorps msn.L, anticorps moes, anticorps Msn

Sujet: Recognizes 78  kDa moesin protein. Moesin, a member of the Talin-4.1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

ID gène: 4478

UniProt: P26038

Pathways: Asymmetric Protein Localization