CYLD anticorps
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- Antigène Voir toutes CYLD Anticorps
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CYLD est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Protein A affinity chromatography
- Immunogène
- A recombinant protein fragment from the N-termiinal region of human CYLD was used as the immunogen for this antibody.
- Isotype
- IgG
- Top Product
- Discover our top product CYLD Anticorps primaire
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anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 170-338) antibody
CYLD Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 654-953) antibodyCYLD Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (C-Term) antibodyCYLD Reactivité: Humain, Souris WB, ICC, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 204-358) antibodyCYLD Reactivité: Humain WB, ELISA, FACS Hôte: Souris Monoclonal 5F7F4 unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 269-435), (C-Term) antibodyCYLD Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (pSer418) antibodyCYLD Reactivité: Humain, Souris WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 32-45) antibodyCYLD Reactivité: Humain, Souris, Hamster, Cobaye, Cheval, Singe, Poulet, Lapin, Boeuf (Vache), Chien WB, ICC Hôte: Lapin Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 305-582) antibodyCYLD Reactivité: Humain WB, FACS Hôte: Souris Monoclonal 1667CT857-3-6-1 unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) antibodyCYLD Reactivité: Humain, Souris, Rat ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 854-953) antibodyCYLD Reactivité: Humain ELISA, IF Hôte: Souris Monoclonal 2C3 unconjugated
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- Indications d'application
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Western blot: 2-5 μg/mL
Provided assay concentrations are suggestions only, CYLD antibody titration may be required for optimal results. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Antigène
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
- Autre désignation
- CYLD (CYLD Produits)
- Synonymes
- anticorps BRSS, anticorps CDMT, anticorps CYLD1, anticorps CYLDI, anticorps EAC, anticorps MFT, anticorps MFT1, anticorps SBS, anticorps TEM, anticorps USPL2, anticorps 2010013M14Rik, anticorps 2900009M21Rik, anticorps C130039D01Rik, anticorps mKIAA0849, anticorps cyld, anticorps LRRGT00003, anticorps Rp1, anticorps Rp1h, anticorps CYLD lysine 63 deubiquitinase, anticorps cylindromatosis (turban tumor syndrome), a, anticorps CYLD, anticorps Cyld, anticorps cylda
- Sujet
- CYLD is involved in multiple physiological processes including immune response, osteoclastogenesis and spermatogenesis. It is a tumor suppressor via its negative regulation of NF-kB activation. CYLD is a deubiquitinase, removing ubiquitin chains from tumor-necrosis factor receptor-associated factor 2 (TRAF2) and thereby preventing its activation of IkB, a regulator of NF-kB. NF-kB remains sequestered in the cytoplasm, unable to translocate to the nucleus and initiate cell survival and oncogenetic signaling.
- ID gène
- 1540
- UniProt
- Q9NQC7
- Pathways
- Apoptose, Activation of Innate immune Response
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