Functional Activity: Comitogenic with soluble anti-CD2 and immobilized anti-CD3 mAbs
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD98 antibody to be titered up or down for optimal performance.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Antigène
SLC3A2
(Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))
anticorps 4F2, anticorps 4F2HC, anticorps 4T2HC, anticorps CD98, anticorps CD98HC, anticorps MDU1, anticorps NACAE, anticorps Mdu1, anticorps MGC53951, anticorps slc3a2, anticorps MGC53965, anticorps SLC3A2, anticorps AI314110, anticorps Cd98, anticorps Ly-10, anticorps Ly-m10, anticorps Ly10, anticorps Mgp-2hc, anticorps fc65h12, anticorps wu:fc65h12, anticorps id:ibd1327, anticorps sb:cb519, anticorps wu:fe14a07, anticorps wu:fq18d12, anticorps zgc:55813, anticorps solute carrier family 3 member 2, anticorps solute carrier family 3 (amino acid transporter heavy chain), member 2 L homeolog, anticorps solute carrier family 3 (amino acid transporter heavy chain), member 2 S homeolog, anticorps solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2, anticorps solute carrier family 3 (amino acid transporter heavy chain), member 2a, anticorps solute carrier family 3 (amino acid transporter heavy chain), member 2b, anticorps SLC3A2, anticorps Slc3a2, anticorps slc3a2.L, anticorps slc3a2.S, anticorps slc3a2a, anticorps slc3a2b
Sujet
CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.