anticorps apg4b, anticorps APG4B, anticorps AUTL1, anticorps 2510009N07Rik, anticorps AW048066, anticorps Apg4b, anticorps Atg4bl, anticorps Autl1, anticorps Aut2b2, anticorps autophagy related 4B cysteine peptidase, anticorps autophagy-related 4b, anticorps Peptidase family C54 protein, anticorps cysteine protease ATG4B, anticorps ATG4 autophagy related 4 homolog B (S. cerevisiae), anticorps autophagy related 4B, cysteine peptidase, anticorps autophagy related 4B, cysteine peptidase L homeolog, anticorps ATG4B, anticorps Atg4b, anticorps AT3G59950, anticorps Tsp_08582, anticorps Tsp_11599, anticorps atg4b, anticorps atg4b.L
Sujet
Autophagy is the cellular mechanism of degradation and turnover of unnecessary or dysfunctional cellular components. The unneeded components are engulfed in vesicles called autophagosomes, where they are broken down and recycled. The 'autophagy-related gene' ATG4B is a regulator of autophagasome maturation. The microtubule-associated protein LC3-I is lipidated (called LC3-II in its lipidated state) and recruited to the autophagosomal membrane where it is of vital importance in the maturation of autophagosomes. ATG4B regulates LC3-II availability by modulating LC3-I lipidation.