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CD27 anticorps

CD27 Reactivité: Humain FACS, IF Hôte: Souris Monoclonal 203-6 unconjugated

N° du produit ABIN6252761

Fiche de données

Antigène Voir toutes CD27 Anticorps

CD27 (CD27 Molecule (CD27))
Reactivité
186

60

46

6

6

6

3

2

1

1

1
Humain
Hôte
104

87

14

11

3

1
Souris
Anticorps secondaires appropriés
Clonalité
130

88

2
Monoclonal
Conjugué
73

22

22

13

11

7

6

5

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Cet anticorp CD27 est non-conjugé
Application
142

84

50

35

33

17

16

13

13

13

11

7

6

4

4

3

3

2

2

2

2

2

1

1

1

1

1
Flow Cytometry (FACS), Immunofluorescence (IF)

Purification

Protein G affinity chromatography

Immunogène

Sezary cells were used as the immunogen for the CD27 antibody.

Clone

203-6

Isotype

IgG3 kappa

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Indications d'application

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 0.5-1 μg/mL

Optimal dilution of the CD27 antibody should be determined by the researcher.

Restrictions

For Research Use only
Format

Liquid

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Aliquot and Store at -20C. Avoid freez-thaw cycles.
Antigène

CD27 (CD27 Molecule (CD27))

Autre désignation

CD27 (CD27 Produits)

Synonymes

anticorps TNFRSF7, anticorps S152, anticorps Tnfrsf7, anticorps Tp55, anticorps S152. LPFS2, anticorps T14, anticorps CD27 molecule, anticorps CD27 antigen, anticorps CD27, anticorps Cd27

Sujet

Recognizes a protein of a disulfide-linked 120  kDa dimer, identified as CD27 (Workshop VI, Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

ID gène

939

UniProt

P26842

Pathways

Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints