p53 anticorps

N° du produit ABIN6253959

Cet anticorps Souris Monoclonal détecte spécifiquement p53 dans FACS et ICC. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour p53 anticorps (ABIN6253959)

Antigène: p53 (TP53) (Tumor Protein P53 (TP53))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp p53 est non-conjugé

Application: Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: BP53-12

Détail du produit anti-p53 anticorps

Specificité: BP53-12, produces mouse IgG2a immunoglobulins recognizes both wild and mutant forms of 53 kD protein, identified as p53 suppressor gene

Pureté: PURE

Isotype: IgG2a

Information d'application

Indications d'application: immunohistochemistry on paraffin tissue sections

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C

Détails sur p53

Antigène: p53 (TP53) (Tumor Protein P53 (TP53))

Autre désignation: p53

Sujet: Antigen distribution: p53 is a tumor suppressor gene encoding a nuclear phosphoprotein that plays an important role in the control of normal cell proliferation. p53 is expressed in peripheral blood and bone marrow cells of patents with some hematological malignance. p53 protein quantitation is of value to ascertain malignancy and provides additional parameter suitable for evaluation of residual disease and for the monitoring of therapy and might also be one of the methods to indicate early relapse [1]. Cellular Expression: Human carcinoma.

Pathways: Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg