p53 anticorps (C-Term)

N° du produit ABIN6254175

Cité dans 1 publication. Cet anticorps anti-p53 Polyclonal Chèvre (ABIN6254175) détecte spécifiquement p53 dans WB et IF. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Singe, Chien, Hamster, Boeuf (Vache), Poulet, Porc, Lapin, Cheval, Mouton, Cat, Cobaye, Chévre, Avian et Âne.

Aperçu rapide pour p53 anticorps (C-Term) (ABIN6254175)

Antigène: p53 (TP53) (Tumor Protein P53 (TP53))

Reactivité: Humain, Souris, Rat, Singe, Chien, Hamster, Boeuf (Vache), Poulet, Porc, Lapin, Cheval, Mouton, Cat, Cobaye, Chévre, Avian, Âne

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp p53 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-p53 anticorps

Épitope: C-Term

Fonction: Anti-P53

Séquence: DRRTEEENLR KKGEPHHELP PGSTKRALPN NTSSSPQPKK KPLDGEYFTL QIRGRERFEM FRELNEALEL KDAQAGKEPG GSRAHSSHLK SKKGQSTSRH KKLMFKTEGP DSD

Specificité: Detects endogenous levels of P53 by Western blot.

Attributs du produit: Tumor protein p53

Purification: Epitope affinity purified

Immunogène: Purified recombinant peptide derived from within residues 280 aa to the C-terminus of human P53 produced in E. coli.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:2,000, IF:1:50-1:250

Restrictions: For Research Use only

Stockage

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody solution should be gently mixed before use.

Stock: 4 °C,-20 °C

Stockage commentaire: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Références pour anticorps anti-p53 (ABIN6254175)

Ferreira, Rosa Soares, Ramalho, Ribeiro-Rodrigues, Máximo, Zuzarte, Girão, Pereira: "Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis." dans: PLoS ONE, Vol. 14, Issue 10, pp. e0223790, (2020) (PubMed).

Détails sur p53

Antigène: p53 (TP53) (Tumor Protein P53 (TP53))

Autre désignation: P53

Sujet:

Goat polyclonal antibody to P53. This protein reacts to diverse cellular stresses to regulate target genes that induce apoptosis, senescence, cell cycle arrest, DNA repair, or changes in metabolism. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is assumed to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumour suppressor.

BCC7, LFS1 and TRP53 antibody.

Pathways: Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg