ARFGAP1 anticorps (Internal Region)

N° du produit ABIN6257929

Détail du produit anti-ARFGAP1 anticorps

Antigène: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARFGAP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: ARFGAP1 Antibody detects endogenous levels of total ARFGAP1.

Homologie: Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ARFGAP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ARFGAP1

Antigène: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Autre désignation: ARFGAP1 (ARFGAP1 Produits)

Synonymes: anticorps ARF1GAP, anticorps HRIHFB2281, anticorps AI115377, anticorps Arf1gap, anticorps Arf GAP1, anticorps arf1gap, anticorps atfb1, anticorps atfb3, anticorps jlns1, anticorps k(v)7.1, anticorps kcna8, anticorps kcna9, anticorps kv1.9, anticorps kv7.1, anticorps kvlqt1, anticorps lqt, anticorps lqt1, anticorps rws, anticorps sqt2, anticorps wrs, anticorps ARFGAP3, anticorps ADP ribosylation factor GTPase activating protein 1, anticorps ADP-ribosylation factor GTPase activating protein 1, anticorps ADP ribosylation factor GTPase activating protein 1 S homeolog, anticorps putative ADP-ribosylation factor GTPase activating protein 1, anticorps ATP-dependent RNA helicase DBP9, anticorps ARFGAP1, anticorps Arfgap1, anticorps arfgap1.S, anticorps Tb11.01.6060, anticorps arfgap1, anticorps LMJF_32_1230, anticorps MGYG_02419

Sujet:

Description: GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine (By similarity).

Gene: ARFGAP1

Poids moléculaire: 60/48 kDa

ID gène: 55738

UniProt: Q8N6T3

Pathways: Signalisation p53, ER-Nucleus Signaling, Unfolded Protein Response