ARFGAP1 anticorps (C-Term)

N° du produit ABIN388996

Détail du produit anti-ARFGAP1 anticorps

Antigène: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Épitope: AA 377-406, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARFGAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This ARFGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-406 amino acids from the C-terminal region of human ARFGAP1.

Clone: RB4855

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:8000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-ARFGAP1 (ABIN388996)

Nishimura, Uchida, Yachi, Kudlyk, Lupashin, Inoue, Taguchi, Arai: "Oxysterol-binding protein (OSBP) is required for the perinuclear localization of intra-Golgi v-SNAREs." dans: Molecular biology of the cell, Vol. 24, Issue 22, pp. 3534-44, (2013) (PubMed).

Zhang, Major, Takanashi, Camp, Nishiya, Peters, Ginsberg, Jian, Randazzo, Schultz, Moon, Ding: "Small-molecule synergist of the Wnt/beta-catenin signaling pathway." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 18, pp. 7444-8, (2007) (PubMed).

Détails sur ARFGAP1

Antigène: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Autre désignation: ARFGAP1 (ARFGAP1 Produits)

Synonymes: anticorps ARF1GAP, anticorps HRIHFB2281, anticorps AI115377, anticorps Arf1gap, anticorps Arf GAP1, anticorps arf1gap, anticorps atfb1, anticorps atfb3, anticorps jlns1, anticorps k(v)7.1, anticorps kcna8, anticorps kcna9, anticorps kv1.9, anticorps kv7.1, anticorps kvlqt1, anticorps lqt, anticorps lqt1, anticorps rws, anticorps sqt2, anticorps wrs, anticorps ARFGAP3, anticorps ADP ribosylation factor GTPase activating protein 1, anticorps ADP-ribosylation factor GTPase activating protein 1, anticorps ADP ribosylation factor GTPase activating protein 1 S homeolog, anticorps putative ADP-ribosylation factor GTPase activating protein 1, anticorps ATP-dependent RNA helicase DBP9, anticorps ARFGAP1, anticorps Arfgap1, anticorps arfgap1.S, anticorps Tb11.01.6060, anticorps arfgap1, anticorps LMJF_32_1230, anticorps MGYG_02419

Sujet: ARFGAP1 is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine.

Poids moléculaire: 44668

ID gène: 55738

NCBI Accession: NP_001268411, NP_001268412, NP_001268413, NP_060679, NP_783202

UniProt: Q8N6T3

Pathways: Signalisation p53, ER-Nucleus Signaling, Unfolded Protein Response