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Glucagon Receptor anticorps (Internal Region)

GCGR Reactivité: Humain, Rat, Souris WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6258919
  • Antigène Voir toutes Glucagon Receptor (GCGR) Anticorps
    Glucagon Receptor (GCGR)
    Épitope
    • 16
    • 8
    • 8
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    • 55
    • 25
    • 24
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    Humain, Rat, Souris
    Hôte
    • 53
    • 1
    • 1
    Lapin
    Clonalité
    • 54
    • 1
    Polyclonal
    Conjugué
    • 21
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Glucagon Receptor est non-conjugé
    Application
    • 40
    • 23
    • 18
    • 13
    • 13
    • 12
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    GLR Antibody detects endogenous levels of total GLR.
    Homologie
    Pig,Bovine,Horse,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human GLR, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product GCGR Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    Glucagon Receptor (GCGR)
    Autre désignation
    GCGR (GCGR Produits)
    Synonymes
    anticorps GCGR, anticorps GGR, anticorps GR, anticorps glucagon receptor, anticorps GCGR, anticorps Gcgr
    Sujet

    Description: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.

    Gene: GCGR

    Poids moléculaire
    54 kDa
    ID gène
    2642
    UniProt
    P47871
    Pathways
    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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