RRAGB anticorps (Internal Region)

N° du produit ABIN6259180

Détail du produit anti-RRAGB anticorps

Antigène: RRAGB (Ras-Related GTP Binding B (RRAGB))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRAGB est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: RRAGB Antibody detects endogenous levels of total RRAGB.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RRAGB, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur RRAGB

Antigène: RRAGB (Ras-Related GTP Binding B (RRAGB))

Autre désignation: RRAGB (RRAGB Produits)

Synonymes: anticorps RAGB, anticorps bA465E19.1, anticorps Ragb, anticorps RRAGB, anticorps Ras related GTP binding B, anticorps Ras-related GTP binding B, anticorps RRAGB, anticorps RragB, anticorps Rragb

Sujet:

Description: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.

Gene: RRAGB

Poids moléculaire: 43 kDa

ID gène: 10325

UniProt: Q5VZM2