ABCG8 anticorps (Internal Region)
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- Antigène Voir toutes ABCG8 Anticorps
- ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
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Épitope
- Internal Region
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ABCG8 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificité
- ABCG8 Antibody detects endogenous levels of total ABCG8.
- Homologie
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human ABCG8, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ABCG8 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
- Autre désignation
- ABCG8 (ABCG8 Produits)
- Synonymes
- anticorps DDBDRAFT_0167690, anticorps DDBDRAFT_0191232, anticorps DDB_0167690, anticorps DDB_0191232, anticorps zgc:172358, anticorps GBD4, anticorps STSL, anticorps 1300003C16Rik, anticorps AI114946, anticorps sterolin-2, anticorps ATP binding cassette subfamily G member 8, anticorps ATP-binding cassette sub-family G member 8, anticorps ABC transporter G family protein, anticorps ATP-binding cassette, sub-family G (WHITE), member 8, anticorps ABCG8, anticorps PTRG_02054, anticorps abcG8, anticorps abcg8, anticorps Abcg8
- Sujet
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Description: ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg2+- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:11099417, PubMed:11452359, PubMed:27144356, PubMed:15054092). Required for normal sterol homeostasis (PubMed:11099417, PubMed:11452359, PubMed:15054092). The heterodimer with ABCG5 has ATPase activity (PubMed:16893193, PubMed:20210363, PubMed:27144356).
Gene: ABCG8
- Poids moléculaire
- 76kDa
- ID gène
- 64241
- UniProt
- Q9H221
- Pathways
- Lipid Metabolism
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