ATP6AP1 anticorps (Internal Region)

N° du produit ABIN6260131

Détail du produit anti-ATP6AP1 anticorps

Antigène: ATP6AP1 (ATPase, H+ Transporting, Lysosomal Accessory Protein 1 (ATP6AP1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP6AP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: ATP6AP1 Antibody detects endogenous levels of total ATP6AP1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human ATP6AP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur ATP6AP1

Antigène: ATP6AP1 (ATPase, H+ Transporting, Lysosomal Accessory Protein 1 (ATP6AP1))

Autre désignation: ATP6AP1 (ATP6AP1 Produits)

Synonymes: anticorps 16A, anticorps ATP6IP1, anticorps ATP6S1, anticorps Ac45, anticorps CF2, anticorps VATPS1, anticorps XAP-3, anticorps XAP3, anticorps AC45, anticorps AI316502, anticorps AW108110, anticorps Atp6ip1, anticorps Atp6s1, anticorps C7-1, anticorps mFLJ00383, anticorps H+-ATPase, anticorps ATPase H+ transporting accessory protein 1, anticorps ATPase, H+ transporting, lysosomal accessory protein 1, anticorps plasma membrane ATPase 4, anticorps ATP6AP1, anticorps Atp6ap1, anticorps LOC547525

Sujet:

Description: Accessory subunit of the proton-transporting vacuolar (V)-ATPase protein pump, which is required for luminal acidification of secretory vesicles. Guides the V-type ATPase into specialized subcellular compartments, such as neuroendocrine regulated secretory vesicles or the ruffled border of the osteoclast, thereby regulating its activity. Involved in membrane trafficking and Ca2+-dependent membrane fusion. May play a role in the assembly of the V-type ATPase complex. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).

Gene: ATP6AP1

Poids moléculaire: 52kDa

ID gène: 537

UniProt: Q15904

Pathways: Proton Transport, SARS-CoV-2 Protein Interactome