DACH1 anticorps (Internal Region)
-
- Antigène Voir toutes DACH1 Anticorps
- DACH1 (Dachshund 1 (DACH1))
-
Épitope
- Internal Region
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp DACH1 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- DACH1 Antibody detects endogenous levels of total DACH1.
- Homologie
- Pig,Rabbit,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human DACH1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product DACH1 Anticorps primaire
-
-
- Indications d'application
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
-
- Antigène
- DACH1 (Dachshund 1 (DACH1))
- Autre désignation
- DACH1 (DACH1 Produits)
- Synonymes
- anticorps DACH, anticorps AI182278, anticorps Dac, anticorps Dach, anticorps E130112M23Rik, anticorps dach, anticorps dachshund family transcription factor 1, anticorps dachshund 1 (Drosophila), anticorps dachshund family transcription factor 1 S homeolog, anticorps dachshund homolog 1, anticorps DACH1, anticorps Dach1, anticorps dach1.S, anticorps dach1, anticorps LOC100550020
- Sujet
-
Description: Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter (By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain (By similarity).
Gene: DACH1
- Poids moléculaire
- 97-100 kDa
- ID gène
- 1602
- UniProt
- Q9UI36
- Pathways
- Feeding Behaviour
-