EDEM2 anticorps

N° du produit ABIN6261430

Détail du produit anti-EDEM2 anticorps

Antigène: EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EDEM2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: EDEM2 Antibody detects endogenous levels of total EDEM2

Réactivité croisée: Humain

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human EDEM2

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur EDEM2

Antigène: EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))

Autre désignation: EDEM2 (EDEM2 Produits)

Synonymes: anticorps C20orf31, anticorps C20orf49, anticorps bA4204.1, anticorps 9530090G24Rik, anticorps AI327354, anticorps RGD1303074, anticorps MGC88910, anticorps DKFZp459A0314, anticorps ER degradation enhancing alpha-mannosidase like protein 2, anticorps ER degradation enhancer, mannosidase alpha-like 2, anticorps EDEM2, anticorps Edem2, anticorps edem2

Sujet:

Description: Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.

Gene: EDEM2

Poids moléculaire: 65 kDa

ID gène: 55741

UniProt: Q9BV94